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Journal of Clinical Endocrinology & Metabolism, Vol 40, 736-737, Copyright © 1975 by Endocrine Society


ARTICLES

Somatomedin activity in cerebrospinal fluid

GR Beaton, J Sagel and LA Distiller

Somatomedin activity has been demonstrated in the cerebrospinal fluid (CSF) of 12 normal subjects and one patient with acromegaly. In all cases the concentration was lower in the CSF than in the corresponding serum, and a significant correlation was demonstrated between the somatomedin activity in the two body fluids (p smaller than 0.01).


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M Berelowitz, M Szabo, L. Frohman, S Firestone, L Chu, and R. Hintz
Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary
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[Abstract] [PDF]




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