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*APOMORPHINE
*GLUCOSE

Journal of Clinical Endocrinology & Metabolism, Vol 40, 1094-1098, Copyright © 1975 by Endocrine Society


ARTICLES

Effectof sex, oral contraceptives, and glucose loading on apomorphine- induced growth hormone secretion

P Ettigi, S Lal, JB Martin and HG Friesen

Apomorphine-induced growth hormone (GH) secretion less in women either on or off oral contraceptives than in men. Women on oral contraceptives have a significantly greater peak GH response to apomorphine than women on no medication. The reason for these differences is unclear. Prior glucose loading in men significantly decreases the GH response to apomorphine. This suggests that stimulation of glucoreceptors antagonises dopaminergic modulation of GH secretion.


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N.R. Best, M.P. Rees, D.H. Barlow, and P.J. Cowen
Effect of oestradiol treatment on 5-HT and dopamine-mediated neuroendocrine responses
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[Abstract] [PDF]




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