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Journal of Clinical Endocrinology & Metabolism, Vol 47, 914-917, Copyright © 1978 by Endocrine Society

ARTICLES

Release of immunoassayable prostaglandin E by the human ischemic kidney

RD Zipser, PF Speckart, PK Zia, JA Hahn, WP Boswell and R Horton

Immunoassayable prostaglandin E concentration in renal venous plasma was measured in eight patients with renovascular hypertension. Two subjects with bilateral renal artery stenosis had similar concentrations from both renal veins. The six subjects with unilateral artery stenosis had greater concentration on the stenotic side in each case, suggesting that the human ischemic kidney produces increased amounts of prostaglandins.


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K. L. Therland, J. Stubbe, H. C. Thiesson, P. D. Ottosen, S. Walter, G. L. Sorensen, O. Skott, and B. L. Jensen
Cycloxygenase-2 Is Expressed in Vasculature of Normal and Ischemic Adult Human Kidney and Is Colocalized with Vascular Prostaglandin E2 EP4 Receptors
J. Am. Soc. Nephrol., May 1, 2004; 15(5): 1189 - 1198.
[Abstract] [Full Text] [PDF]


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