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Journal of Clinical Endocrinology & Metabolism, Vol 47, 918-921, Copyright © 1978 by Endocrine Society

ARTICLES

Progesterone induced acute release of prolactin in estrogen primed ovariectomized women

JS Rakoff and SS Yen

Progesterone (10 mg) administered intramuscularly induces a concurrent release of prolactin as well as gonadotropin in estrogen-primed women. The time course of pituitary release of all three of these hormones appears to include a latent phase of 4 hrs and is maintained for at least 5 hrs. It is considered that this effect of progesterone may be mediated through a reduction of hypothalamic dopamine.




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Copyright © 1978 by The Endocrine Society