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Journal of Clinical Endocrinology & Metabolism, Vol 48, 869-871, Copyright © 1979 by Endocrine Society

ARTICLES

Hemodialysis-resistant hypertension: control with an orally active inhibitor of angiotensin-converting enzyme

ED Vaughan Jr, RM Carey, CR Ayers and MJ Peach

In two patients with end stage renal disease and dialysis-resistant hypertension, the orally active inhibitor of angiotensin-converting enzyme, captopril (SQ14,225; 2-D-methyl-3-mercaptopropranoyl-L-proline, dramatically lowered blood pressure both before and during dialysis. This agent holds promise as an alternate to bilateral nephrectomy in such patients.




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Endocrinology Endocrine Reviews J. Clin. End. & Metab.
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Copyright © 1979 by The Endocrine Society