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Journal of Clinical Endocrinology & Metabolism, Vol 48, 1033-1034, Copyright © 1979 by Endocrine Society

ARTICLES

Plasma testosterone and the diagnosis of panhypopituitarism in women

JP Raymond, J Predine, RE Merceron, E Milgrom and HP Klotz

Plasma testosterone was shown to be a very sensitive index of panhypopituitarism in women. In 18 women, testosterone levels were found to be 0.06 +/- 0.04 ng/ml (mean +/- SD; normal, 0.40 +/- 0.10 ng/ml). In all patients, the values were below 2 SD of testosterone levels found in normal women. Dihydrotestosterone concentrations were similarly modified. Such an important decrease in plasma testosterone was probably due to the additional effect produced by the functional suppression of both sources of testosterone precursors: the adrenals and the ovaries.


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K. K. Miller, G. Sesmilo, A. Schiller, D. Schoenfeld, S. Burton, and A. Klibanski
Androgen Deficiency in Women with Hypopituitarism
J. Clin. Endocrinol. Metab., February 1, 2001; 86(2): 561 - 567.
[Abstract] [Full Text]


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