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Recurrent Cushing’s Syndrome Due to Recurrent Adrenocortical Tumor—Fragmentation or Tumor in Ectopic Adrenal Tissue?

Division of Endocrinology, Bronfman Department of Medicine, Mount Sinai Hospital and Mount Sinai School of Medicine of the City University of New York, New York, New York 10029

Address all correspondence and requests for reprints to: Dr. J. Lester Gabrilove, Division of Endocrinology, Mount Sinai School of Medicine, 5th Avenue and 100th Street, New York, New York 10029.

A 33-yr-old woman was found to have Cushing’s syndrome due to a left adrenal cortical tumor. The tumor and the surrounding adrenal gland were removed intact and in toto. Four years later, she noticed recurrent symptoms of Cushing’s syndrome, and 6 yr postoperatively, an adrenal tumor was demonstrable on computed tomography. Fourteen years after the initial procedure, a left adrenal tumor, presumably arising in ectopic adrenal tissue, was removed with relief of her symptoms of Cushing’s syndrome. The site and functional capacity of ectopic adrenal tissues are reviewed.

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