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University of Manchester, Departments of Medicine and Gastroenterology, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom
Address all correspondence and requests for reprints to: P. N. Durrington, Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, United Kingdom.
We describe a dramatic response to antioxidant therapy in three patients with familial lipoprotein lipase deficiency complicated by frequent severe episodes of pancreatitis who had failed to respond to other dietary and pharmacological measures. Antoxidant therapy may be an important advance in the management of this type of patient.
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M.-a. Kawashiri, T. Higashikata, M. Mizuno, M. Takata, S. Katsuda, K. Miwa, T. Nozue, A. Nohara, A. Inazu, J. Kobayashi, et al. Long-Term Course of Lipoprotein Lipase (LPL) Deficiency Due to Homozygous LPLArita in a Patient with Recurrent Pancreatitis, Retained Glucose Tolerance, and Atherosclerosis J. Clin. Endocrinol. Metab., December 1, 2005; 90(12): 6541 - 6544. [Abstract] [Full Text] [PDF] |
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M. M. Hoffmann, S. Jacob, D. Luft, R.-M. Schmülling, K. Rett, W. März, H.-U. Häring, and S. Matthaei Type I Hyperlipoproteinemia Due to a Novel Loss of Function Mutation of Lipoprotein Lipase, Cys239{->}Trp, Associated with Recurrent Severe Pancreatitis J. Clin. Endocrinol. Metab., December 1, 2000; 85(12): 4795 - 4798. [Abstract] [Full Text] |
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