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This version published online on June 3, 2008
Journal of Clinical Endocrinology & Metabolism, doi:10.1210/jc.2008-0660
A more recent version of this article appeared on August 1, 2008
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Submitted on March 24, 2008
Accepted on May 22, 2008

Clinical and Economic Outcomes of Thyroid and Parathyroid Surgery in Children

Julie Ann Sosa MA MD, Charles T. Tuggle BS, Tracy S. Wang MD MPH*, Daniel C. Thomas BS, Leon Boudourakis BS, Scott Rivkees MD, and Sanziana A. Roman MD

Department of Surgery, Yale University School of Medicine, New Haven, Connecticut; Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin; Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut

* To whom correspondence should be addressed. E-mail: tswang{at}mcw.edu.

Context: Clinical and economic outcomes after thyroidectomy/parathyroidectomy in adults have demonstrated disparities based on patient age and race/ethnicity; there is a paucity of literature on pediatric endocrine outcomes.

Objective: The objective was to examine the clinical and demographic predictors of outcomes following pediatric thyroidectomy/parathyroidectomy.

Design: This study is a cross-sectional analysis of Healthcare Cost and Utilization Project –National Inpatient Sample hospital discharge information from 1999–2005. All patients who underwent thyroidectomy/parathyroidectomy were included. Bivariate and multivariate analyses were performed to identify independent predictors of patient outcomes.

Subjects: 1,199 patients ≤ 17 years undergoing thyroidectomy/parathyroidectomy.

Main outcome measure: In-hospital patient complications, length of stay (LOS), and inpatient hospital costs.

Results: The majority of patients were female (76%), aged 13–17 years (71%), and white (69%). Whites were more often in the highest income group (80% vs. 8%Hispanic, 6%black;P<0.01) and had private/HMO insurance (76% vs. 10%Hispanic, 5%black;P<0.001) rather than Medicaid (13% vs. 32%Hispanic, 41%black;P<0.001). 91% of procedures were thyroidectomies, 9% parathyroidectomies. Children aged 0–6 years had higher complication rates (22% vs. 15% 7–12years, 11% 13–17years;P<0.01), LOS (3.3days vs. 2.3, 7–12years, 1.8, 13–17years;P<0.01), and higher costs. Compared to children from higher income families, those from lower income families had higher complication rates (11.5% vs. 7.7%;P<0.05), longer LOS (2.7days vs. 1.7;P<0.01), and higher costs. Children had higher endocrine-specific complication rates than adults following parathyroidectomy (15.2% vs. 6.2%;P<0.01) and thyroidectomy (9.1% vs. 6.3%;P<0.01).

Conclusions: Children undergoing thyroidectomy/parathyroidectomy have higher complication rates than adult patients. Outcomes were optimized when surgeries were performed by high-volume surgeons. There appears to be disparity in access to high-volume surgeons for children from low-income families, blacks, and Hispanics.


Key words: Pediatric • thyroidectomy • parathyroidectomy • outcomes







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