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JCEM & Pfizer Awards

The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in JCE&M was established by The Endocrine Society in 2000, through the generous support of Pfizer, Inc. This award recognizes the four best clinical research papers that appear in The Journal of Clinical Endocrinology & Metabolism (JCEM) for the previous year. The purpose of this award is to encourage, recognize and reward excellence in clinical research in endocrinology. Four awards at $10,000 each are awarded annually. Supported by Pfizer, Inc.

2009 The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2008

FINALIST AWARDS:

"Acyl and Total Ghrelin Are Suppressed Strongly by Ingested Proteins, Weakly by Lipids, and Biphasically by Carbohydrates." Vol. 93, No. 5, p. 1971-1979.

Authors: Karen E. Foster-Schubert, Joost Overduin, Catherine E. Prudom, Jianhua Liu, Holly S. Callahan, Bruce D. Gaylinn, Michael O. Thorner, and David E. Cummings

"Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency." Vol. 93, No. 10, p. 3827-3832.

Authors: Gareth G. Lavery, Elizabeth A. Walker, Ana Tiganescu, Jon P. Ride, Cedric H. L. Shackleton, Jeremy W. Tomlinson, John M. C. Connell, David W. Ray, Anna Biason-Lauber, Ewa M. Malunowicz, Wiebke Arlt, and Paul M. Stewart

"Prospective Study of High-Dose Cabergoline Treatment of Prolactinomas in 150 Patients." Vol. 93, No. 12, p. 4721-4727.

Authors: Masami Ono, Nobuhiro Miki, Takakazu Kawamata, Rena Makino, Kosaku Amano, Toshiro Seki, Osami Kubo, Tomokatsu Hori, and Kazue Takano

"Prevention of Diabetes in Women with a History of Gestational Diabetes: Effects of Metformin and Lifestyle Interventions." Vol. 93, No. 12, p. 4774-4779.

Authors: Robert E. Ratner, Costas A. Christophi, Boyd E. Metzger, Dana Dabelea, Peter H. Bennett, Xavier Pi-Sunyer, Sarah Fowler, Steven E. Kahn The Diabetes Prevention Program Research Group

2008 The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2007

FINALIST AWARDS:

"Neuroendocrine Phenotype Analysis in Five Patients with Isolated Hypogonadotropic Hypogonadism due to a L102P Inactivating Mutation of GPR54." Vol. 92, No. 3, p. 1137-1144.

Authors: Yardena Tenenbaum-Rakover, Monique Commenges-Ducos, André Iovane, Chantal Aumas, Osnat Admoni and Nicolas de Roux

"The Influence of Selenium Supplementation on Postpartum Thyroid Status in Pregnant Women with Thyroid Peroxidase Autoantibodies." Vol. 92, No. 4, 1263-1268.

Authors: Roberto Negro, Gabriele Greco, Tiziana Mangieri, Antonio Pezzarossa, Davide Dazzi and Haslinda Hassan

Single Serum Activin A Testing to Predict Ectopic Pregnancy." Vol. 92, No. 5, p. 1748-1753.

Authors: Pasquale Florio, Filiberto Maria Severi, Caterina Bocchi, Stefano Luisi, Massimo Mazzini, Secondo Danero, Michela Torricelli and Felice Petraglia

11p15 Imprinting Center Region 1 Loss of Methylation Is a Common and Specific Cause of Typical Russell-Silver Syndrome: Clinical Scoring System and Epigenetic-Phenotypic Correlations." Vol. 92, No. 8, p. 3148-3154.

Authors: Irène Netchine, Sylvie Rossignol1, Marie-Noëlle Dufourg, Salah Azzi, Alexandra Rousseau, Laurence Perin, Muriel Houang, Virginie Steunou, Blandine Esteva, Nathalie Thibaud, Marie-Charles Raux Demay, Fabienne Danton, Elzbieta Petriczko, Anne-Marie Bertrand, Claudine Heinrichs, Jean-Claude Carel, Guy-André Loeuille, Graziella Pinto, Marie-Line Jacquemont, Christine Gicquel, Sylvie Cabrol and Yves Le Bouc

2007 The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2006

FINALIST AWARDS:

"Radioiodine Ablation of Thyroid Remnants after Preparation with Recombinant Human Thyrotropin in Differentiated Thyroid Carcinoma: Results of an International, Randomized, Controlled Study." Vol. 91, No. 3, p. 926-932.

Authors: F. Pacini, P. W. Ladenson, M. Schlumberger, A. Driedger, M. Luster, R. T. Kloos, S. Sherman, B. Haugen, C. Corone, E. Molinaro, R. Elisei, C. Ceccarelli, A. Pinchera, R. L. Wahl, S. Leboulleux, M. Ricard, J. Yoo, N. L. Busaidy, E. Delpassand, H. Hanscheid, R. Felbinger, M. Lassmann, and C. Reiners

"Effects of Testosterone Replacement in Androgen-Deficient Women with Hypopituitarism: A Randomized, Double-Blind, Placebo-Controlled Study." Vol. 91, No. 5. p. 1683-1690.

Authors: K. K. Miller, B. M. K. Biller, C. Beauregard, J. G. Lipman, J. Jones, D. Schoenfeld, J. C. Sherman, B. Swearingen, J. Loeffler, and A. Klibanski

"Levothyroxine Treatment in Euthyroid Pregnant Women with Autoimmune Thyroid Disease: Effects on Obstetrical Complications." Vol. 91, No. 7, p. 2587-2591.

Authors: Roberto Negro, Gianni Formoso, Tiziana Mangieri, Antonio Pezzarossa, Davide Dazzi, and Haslinda Hassan

"Thiazolidinedione Use and Bone Loss in Older Diabetic Adults." Vol. 91, No. 9, p. 3349-3354

Authors: Ann V. Schwartz, Deborah E. Sellmeyer, Eric Vittinghoff, Lisa Palermo, Beata Lecka-Czernik, Kenneth R. Feingold, Elsa S. Strotmeyer, Helaine E. Resnick, Laura Carbone, Brock A. Beamer, Seok Won Park, Nancy E. Lane, Tamara B. Harris, Steven R. Cummings for the Health, Aging and Body Composition (Health ABC) Study

2006 The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2005

FINALIST AWARDS:

"Fibroblast Growth Factor 7: An Inhibitor of Phosphate Transport Derived from Oncogenic Osteomalacia-Causing Tumors." Vol. 90, No. 2, p. 1012-1020.

Authors: Thomas O. Carpenter, Bruce K. Ellis, Karl L. Insogna, William M. Philbrick, John Sterpka, and Richard Shimkets

"Genetic Classification of Benign and Malignant Thyroid Follicular Neoplasia Based on a Three-Gene Combination" Vol. 90, No. 5, p. 2512-2521.

Authors: Frank Weber, Lei Shen, Micheala A. Aldred, Carl D. Morrison, Andrea Frilling, Motoyasu Saji, Frank Schuppert, Christoph E. Broelsch, Matthew D. Ringel, and Charis Eng

"High Sensitivity of Human Melatonin, Alertness, Thermoregulation, and Heart Rate to Short Wavelength Light" Vol. 90, No. 3, p. 1311-1316.

Authors: Christian Cajochen, Mirjam Münch, Szymon Kobialka, Kurt Kräuchi, Roland Steiner, Peter Oelhafen, Selim Orgül and Anna Wirz-Justice

"Kisspeptin-54 Stimulates the Hypothalamic-Pituitary Gonadal Axis in Human Males" Vol. 90, No. 12, p. 6609-6615.

Authors: Waljit S. Dhillo, Owais B. Chaudhri, Michael Patterson, Emily L. Thompson, Kevin G. Murphy, Michael K. Badman, Barbara M. McGowan, Vian Amber, Sejal Patel, Mohammad A. Ghatei and Stephen R. Bloom

2005 The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2004

FINALIST AWARDS:

“X-Chromosome Inactivation Patterns and Androgen Receptor Functionality Influence Phenotype and Social Characteristics as Well as Pharmacogenetics of Testosterone Therapy in Klinefelter Patients.” Vol. 89, No. 12, p. 6208-6217

Authors: Michael Zitzmann, Marion Depenbusch, Jörg Gromoll, and Eberhard Nieschlag

“Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Density in Older Men with Low Serum Testosterone.” Vol. 89, No. 2, p. 503-510

Authors: John K. Amory, Nelson B. Watts, Kirk A. Easley, Paul R. Sutton, Bradley D. Anawalt, Alvin M. Matsumoto, William J. Bremner, and J. Lisa Tenover

“Insulin-Like Growth Factor I Has a Direct Effect on Glucose and Protein Metabolism, But No Effect on Lipid Metabolism in Type 1 Diabetes,” Vol. 89, No. 1, p. 425-432

Authors: Helen L. Simpson, Nicola C. Jackson, Fariba Shojaee-Moradie, Richard H. Jones, David L. Russell-Jones, Peter H. Sönksen, David B. Dunger, and A. Margot Umpleby

“The Effects of Vitamin A Deficiency and Vitamin A Supplementation on Thyroid Function in Goitrous Children,” Vol. 89, No. 11, p. 5441-5447

Authors: Michael B. Zimmermann, Rita Wegmüller, Christophe Zeder, Nourredine Chaouki, and Toni Torresani

2004 The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2003

FIRST PRIZE:

“Luteinizing Hormone Pulsatility Is Disrupted at a Threshold of Energy Availability in Regularly Menstruating Woman,” Vol. 88, No. 1, 2003, p. 297-311

Authors: Anne B. Loucks and Jean R. Thuma

FINALIST:

“A Longer Biological Night in Long Sleepers Than in Short Sleepers,” Vol. 88, No. 1, p. 26-30

Authors: Daniel Aeschbach, Leo Sher, Teodor T. Postolache, Jeffery R. Matthews, Michael A. Jackson, and Thomas A. Wehr

FINALIST:

“Effect of Growth Hormone (GH) Treatment on Bone in Postpubertal GH-Deficient Patients: A 2-Year Randomized, Controlled, Dose-Ranging Study,” Vol. 88, No. 9, p. 4124-4129

Authors: Stephen M. Shalet, Elena Shavrikova, Morris Cromer, Christopher J. Child, Eberhard Keller, Jirina Zapletalova, Thomas Moshang, Werner F. Blum, John J. Chipman, Charmian A. Quigley, and Andrea F. Attanasio

FINALIST:

“Defective Activation of Skeletal Muscle and Adipose Tissue Lipolysis in Type 1 Diabetes Mellitus during Hypoglycemia,” Vol. 88, No. 4, p. 1503-1511

Authors: Staffan Enoksson, Sonia K. Caprio, Frances Rife, Gerald I. Shulman, William V. Tamborlane, and Robert S. Sherwin

2003 The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2002

FIRST PRIZE:

"The Cardiovascular Risk of GH-Deficient Adolescents," Vol. 87, No. 8, 2002, p. 3650-3655

Authors: Annamaria Colao, Carolina Di Somma, Mariacarolina Salerno, Letizia Spinelli, Francesco Orio and Gaetano Lombardi

FIRST PRIZE:

"Adrenal Incidentaloma: A New Cause of the Metabolic Syndrome?," Vol. 87, No.3, 2002. p. 998-1003

Authors: Massimo Terzolo, Anna Pia, Anna Ali, Giangiacomo Osella, Giuseppe Reimondo, Silvia Bovio, Fulvia Daffara, Massimo Procopio, Piero Paccotti, Giorgio Borretta and Alberto Angeli

FINALIST:

"The Effects of Varying Doses of T on Insulin Sensitivity, Plasma Lipids, Apolipoproteins and C-Reactive Protein in Healthy Young Men," Vol. 87, No. 1, 2002, 136-143

Authors: Atam B. Singh, Stanley Hsia, Petar Alaupovic, Indrani Sinha-Hikim, Linda Woodhouse, Thomas A. Buchanan, Ruoquing Shen, Rachelle Bross, Nancy Berman and Shalendar Bhasin

FINALIST:

"Narrow Individual Variations in Serum T4 and T3 in Normal Subjects: A Clue to the Understanding of Subclinical Thyroid Disease." Vol. 87, No. 3, 2002, p. 1068-1072

Authors: Stig Anderson, Klause Michael Pedersen, Niels Henrik Bruun, and Peter Laurberg

2002 The Endocrine Society and Pharmacia Corporation International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2001

FIRST PRIZE

"What are the Physical Characteristics Associated with a Normal Metabolic Profile Despite a High Level of Obesity in Postmenopausal Women?" Vol. 86, No. 3, 2001, p. 1020-1025.

Authors: Martin Brochu, Andre Techernof, Isabelle J. Dionne, Cynthia K. Sites, Georgia H. Eltabbakh, Ethan A. H. Sims and Eric T. Poehlman

FINALISTS

"Insulin Inhibits Intranuclear Nuclear Factor κB and Stimulates IκB in Mononuclear Cells in Obese Subjects: Evidence for an Anti-inflammatory Effect?" Vol. 86, No. 7, 2001, p. 3257-3265.

Authors: Paresh Dandona, Ahmad Aljada, Priya Mohanty, Husam Ghanim, Wael Hamouda, Ezzat Assian, and Shakeel Ahmad

"Differential Regulation of Gonadotropin Secretion by Testosterone in the Human Male: Absence of a Negative Feedback Effect of Testosterone on Follicle-Stimulating Hormone Secretion." Vol. 86, No. 1, 2001, p. 53-58. Authors: Frances J. Hayes, Suzzunne DeCruz, Stephanie B. Seminara, Paul A. Boepple, and William F. Crowley, Jr.

"TSH-Controlled L-Thyroxine Therapy Reduces Cholesterol Levels and Clinical Symptoms in Subclinical Hypothyroidism: A Double Blind, Placebo-Controlled Trial (Basel Thyroid Study)." Vol. 86, No. 10, 2001, p. 4860-4866.

Authors: Christian Meier, Jean-Jacques Staub, Carl-Bénédict Roth, Merih Guglielmetti, Maya Kunz, André R. Miserez, Jürgen Drewe, Peter Huber, Richard Herzog, and Beat Müller

2001 The Endocrine Society/Pharmacia Corporation International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 2000

FIRST PRIZE

"Direct Measurement of Pulsatile Insulin Secretion from the Portal Vein in Human Subjects." Vol. 85, No. 12, 2000, p. 4491-4499.

Authors: Soon H. Song, Susan S. McIntyre, Hasnain Shah, Johannes D. Velhuis, Peter C. Hayes, and Peter C. Butler

FINALISTS

"Polycystic Ovarian Syndrome: Evidence that Flutamide Restores Sensitivity of the Gnadotropin-Releasing Hormone Pulse Generator to Inhibition by Estradiol and Progesterone." Vol. 85, No. 11, 2000, p. 4047-4052.

Authors: Christine A. Eagleson, Melissa B. Gingrich, Carmen L. Pastor, Tania K. Arora, Christine M. Burt, William S. Evans, and John C. Marshall

"Sex-Determining Gene(s) on Distal 9p: Clinical and Molecular Studies in Six Cases." Vol. 85, No. 9, 2000, p. 3094-3100.

Authors: Koji Muroya, Torayuki Okuyama, Keiji Goishi, Yoshifumi Ogiso, Shin Fukuda, Junji Kameyama, Hirokazu Sato, Yoshimi Suzuki, Hiroshi Terasaki, Hiroki Gomyo, Keiko Wakui, Yoshimitsu Fukushima, and Tsutomu Ogata

"Fasting Insulin Levels Influence Plasma Leptin Levels Independently from the Contribution of Adiposity: Evidence from both a Cross-Sectional and an Interventional Study." Vol. 85, No. 11, 2000, p. 4231-4337.

Authors: Eric Doucet, Sylvie St -Pierre, Natalie Almeras, Pascale Mauriege, Jean-Pierre Despres, Denis Richard, Claude Bourchard and Angelo Tremblay

2000 Pharmacia & Upjohn International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism in 1999

FIRST PRIZE

"Metabolic Effects of Short-term Elevations of Plasma Cortisol are More Pronounced in the Evening than in the Morning." Vol. 84, No. 9, 1999, p. 3082-3092.

Authors: Laurence Plat, Rachel Leproult, Mireille L'Hermite-Baleriaux, Frandoise Fery, Jean Mockel, Kenneth S. Polonsky and Eve Van Cauter

FINALISTS

"Anovulation after Precocious Pubarche: Early Markers and Time Course in Adolescence." Vol. 84, No. 8, 1999, p. 2691-2695.

Authors: Lourdes Ibanez, Francis de Zegher, and Neus Potau

"Ovarian Responses in Women to Recombinant Follicle-Stimulating Hormone and Luteinizing Hormone (LH): a Role for LH in the Final Stages of Follicular Maturation." Vol. 84, No. 1, 1999, p. 228-232.

Authors: Michael W. Sullivan, Ann Stewart-Akers, Joel S. Krasnow, Sarah L. Berga, and Anthony J. Zeleznik

"Measures of Submaximal Aerobic Performance Evaluate and Predict Functional Response to Growth Hormone (GH) Treatment in GH-Deficient Adults." Vol. 84, No. 12, 1999, p. 4570-4577.

Authors: Linda J. Woodhouse, Sylvia L. Asa, Scott G. Thomas, and Shereen Ezzat

The 1999 Pharmacia & Upjohn International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology & Metabolism

FIRST PRIZE

"The Aromatase Excess Syndrome Is Associated with Feminization of Both Sexes and Autosomal Dominant Transmission of Aberrant P450 Aromatase Gene Transcription." Vol. 83, No. 4, 1998, p. 1348-1357.

Authors: Constantine A. Stratakis, Alessandra Vottero, Angela Brodie, Lawrence S. Kirschner, David DeAtkine, Qing Lu, Wei Yue, Constantine S. Mitsiades, Armando W. Flor, and George P. Chrousos

FINALISTS

"Relationship of Serum Sex Steroid Levels and Bone Turnover Markers with Bone Mineral Density in Men and Women: A Key Role for Bioavailable Estrogen." Vol. 83, No. 7, 1998, p. 2266-2274.

Authors: Sundeep Khosla, L. Joseph Melton, III, Elizabeth J. Atkinson, W. M. O'Fallon, George G. Klee, and B. Lawrence Riggs

"MK-677, an Orally Active Growth Hormone Secretagogue, Reverses Diet-Induced Catabolism." Vol. 83, No. 2, 1998, p. 320-325.

Authors: M. G. Murphy, L. M. Plunkett, B. J. Gertz, W. He, J. Wittreich, W. M. Polvino, and D. R. Clemmons

".Neuroendocrinology of Prolonged Critical Illness: Effects of Exogenous Thyrotropin-Releasing Hormone and Its Combination with Growth Hormone Secretagogues." Vol. 83, No. 2, 1998, p.309-319.

Authors: Greet Van den Berghe, Francis de Zegher, Robert C. Baxter, Johannes D. Veldhuis, Pieter Wouters, Miet Schetz, Charles Verwaest, Erik Van der Vorst, Peter Lauwers, Roger Bouillon, and Cyril Y. Bowers


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